5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine CAS 398565-53-2 for Abemaciclib Synthesis

Name: "5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine CAS 398565-53-2 for Abemaciclib Synthesis"
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Inventário:

SKU: 690872624X

Modelo: 4-Bromo-2,6-difluoroaniline 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine 2-Bromo-5-formylpyridine 4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Haohong Pharmaceutical

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Product Summary

5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine (CAS 398565-53-2) is a key heterocyclic intermediate used in the synthesis of Abemaciclib. With a purity of ≥98.0% (HPLC) and a well-defined molecular structure, this compound facilitates efficient coupling reactions in API manufacturing.

Key Selling Points

Key Intermediate for Abemaciclib: Directly used in the synthesis of this anticancer drug, ensuring consistent supply for API production.
High Purity ≥98.0% (HPLC): Reduces downstream purification burden and enhances overall yield.
Stable Storage Profile: Sealed, low temperature and light protection ensures stability during transportation and storage.
Defined Molecular Properties: Molecular weight 220.03 and boiling point 368.5°C provide predictable behavior in chemical reactions.
Custom Synthesis Support: Available from gram scale to hundreds of kilograms for R&D and commercial needs.

Technical Specifications

Parameter	Value
CAS Number	398565-53-2
Molecular Formula	C₁₂H₂₀N₄
Molecular Weight	220.03
Appearance	Off-white to light yellow solid
Purity	≥98.0% (HPLC)
Boiling Point	368.5±42.0 °C
Density	1.124±0.06 g/cm³
Storage Conditions	Sealed, low temperature and light protection

Models and Options

Supplied in research and bulk quantities. Custom packaging and COA available on request.

Materials and Structure

Piperazinyl substituted pyridine amine heterocyclic organic compound. The ethylpiperazine moiety is critical for the biological activity of the final drug.

Applications

Pharmaceutical industry, particularly anti-cancer drug synthesis and targeted therapy. Used in the production of Abemaciclib and related research.

FAQ

What is the purity specification?

We provide ≥98.0% purity as determined by HPLC.

What are the storage conditions?

Keep sealed at low temperature and avoid light exposure.

Can you supply for R&D purposes?

Yes, we offer custom synthesis from gram scale upwards.

Do you provide COA?

Yes, each batch is batch-tested and provided with a COA.

What is the lead time for bulk orders?

Lead time depends on quantity and is confirmed upon order.

Inquiry Information

Contact Xu Tianxia at Xutx@haohong-pharma.com or +86 180-6854-1569.